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Tinidazole is a synthetic antiprotozoal agentTinidazole demonstrates activity both in vitro and in clinical infections against the following protozoaTrichomonas vaginalisGiardia duodenalisalso termed Glambliaand Entamoeba histolyticaTinidazole does not appear to have activity against most strains of vaginal lactobacilli.
Because clinical trials are conducted under widely varying conditionsadverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.
Tinidazole is indicated for the treatment of intestinal amebiasis and amebic liver abscess caused by Entamoeba histolytica in both adults and pediatric patients older than three years of ageIt is not indicated in the treatment of asymptomatic cyst passagesee Clinical Studies
Although not specifically identified in studies with tinidazolethe following drug interactions were reported for metronidazolea chemically-related nitroimidazoleThereforethese drug interactions may occur with tinidazole.
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